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Narrowing the spectrum: development of a UK paediatric antimicrobial prescribing summary
  1. Annalie Shears1,
  2. Alicia Demirjian2,3,4,
  3. Orlagh McGarrity5,
  4. Stefania Vergnano6,
  5. Sanjay Valabh Patel7,
  6. Paddy McMaster8
  1. 1 Paediatrics, Manchester University NHS Foundation Trust, Manchester, UK
  2. 2 Paediatric Infectious Diseases and Immunology, Evelina London Children's Hospital, London, UK
  3. 3 Health Associated Infections and Antimicrobial Resistance, UK Health Security Agency, London, UK
  4. 4 Faculty of Life Sciences and Medicine, Kings College London, London, UK
  5. 5 Pharmacy, Evelina London Children's Hospital, London, UK
  6. 6 Paediatric Infectious Diseases and Immunology, University Hospitals Bristol and Weston NHS Foundation Trust, Bristol, UK
  7. 7 Paediatric Infectious Diseases and Immunology, University Hospital Southampton NHS Foundation Trust, Southampton, UK
  8. 8 Paediatric Infectious Diseases, Manchester University NHS Foundation Trust, Manchester, UK
  1. Correspondence to Dr Annalie Shears, Paediatrics, Manchester University NHS Foundation Trust, Manchester M13 9WL, UK; annalieshears{at}gmail.com

http://dx.doi.org/10.1136/archdischild-2022-323858

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    Antimicrobial resistance (AMR) is predicted to kill 10 million people a year by 2050, costing the world up to $100 trillion.1 AMR threatens modern medicine as interventions such as surgery and chemotherapy cannot be provided safely without effective antibiotics. While AMR occurs naturally, modifiable factors contribute to its spread: inappropriate selection of agents and extended duration and spectrum of antimicrobial prescriptions.2 There is wide variation in inpatient paediatric antibiotic prescribing in the UK, with discrepancy between specialist groups, tertiary centres and even between clinicians within a hospital.3 To address this variation in prescribing, the UK Paediatric Antimicrobial Stewardship (UK-PAS) network aimed to reach national consensus by drafting a paediatric antimicrobial summary for hospitals based on the format of the National Institute for …

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    Footnotes

    • Collaborators UK Paediatric Antimicrobial Stewardship Committee.

    • Contributors AS and PM contributed to the writing of the manuscript on behalf of and with the permission of the UK-PAS committee, with input from AD, SV and SVP.

    • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

    • Competing interests AS is an NIHR Academic Clinical Fellow.

    • Provenance and peer review Not commissioned; internally peer reviewed.