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Chronic cough – over stimulation of C-fibres?

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The Archivist has attempted to manage chronic cough in children for a number of decades. It’s always been quite frustrating as various theories have focused on: undertreated cough variant asthma (does this exist anymore?), various immune deficiencies (Ig2 and Ig4 subclass deficiencies or vaccination failures), cough receptor sensitivity variability, gastro-oesophageal reflux, post-nasal drip (is this a cause anymore?), habit cough, chronic bronchitis or protracted bacterial bronchitis (PBB)… the list is endless. Now, the classification into ‘dry cough’ or ‘wet cough’ is useful in working it all out, but we end up with some children with chronic unexplained chronic cough, impacting on school …

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