Table of contents

November 2022 - Volume 107 - 11

Highlights from this issue

  • Atoms (19 October, 2022) Free
    Nick Brown


Global child health

  • Vitamin D deficiency in South-East Asian children: a systematic review (9 June, 2022) Free
    Vicka Oktaria, Dwi Astuti Dharma Putri, Zulfikar Ihyauddin, Madarina Julia, Dian Caturini Sulistyoningrum, Poh Bee Koon, Margaret Danchin, Indah Kartika Murni

    Vitamin D deficiency remains underdiagnosed worldwide, with significant impacts on many aspects of child health. The high rates of seemingly healthy children in southeast Asia commonly suffering from this condition help bring attention to this hidden form of malnutrition.

  • Incidence and aetiology of infant Gram-negative bacteraemia and meningitis: systematic review and meta-analysis (16 June, 2022)
    Luisa K Hallmaier-Wacker, Amelia Andrews, Olisaeloka Nsonwu, Alicia Demirjian, Russell J Hope, Theresa Lamagni, Simon M Collin

    This systematic review confirms the disproportionate burden of Gram negative infections in low and middle income countries, compared to high income countries.

Paediatric emergency medicine

  • Rate of invasive bacterial infection in recently vaccinated young infants with fever without source (27 July, 2022)
    Ana Barreiro-Parrado, Eider Lopez, Borja Gomez, Ainara Lejarzegi, Amaia Fernandez-Uria, Javier Benito, Santiago Mintegi

    This secondary analysis of observational registry data compared the rates of IBI (bacterial pathogen in blood or cerebrospinal fluid) and urinary tract infection (UTI) in febrile infants between 42 and 90 days of age who had and had not been vaccinated in the previous 48 hours and conclude that UTI screening remains appropriate, but with further study the need for IBI screening in recently vaccinated infants could be revisited.


Original research


  • Oral saliva swab reverse transcription PCR for Covid-19 in the paediatric population (10 June, 2022)
    Cinta Moraleda, Sara Domínguez-Rodríguez, Juan Miguel Mesa, Paula García-Sánchez, María de la Serna, José Antonio Alonso-Cadenas, Amanda Bermejo, Gema Sabrido, Leticia Martínez-Campos, Aránzazu Flavia González-Posada, Marta Illán-Ramos, Elena Cobos-Carrascosa, Álvaro Ballesteros, Juan Carlos Galán, Francisco Llorente, David Aguilera-Alonso, Ana Belén Jiménez, Pilar Catalán, Elias Dahdouh, Ignacio Navarro, Bárbara Fernández-Garoz, Pablo Mendoza, Concepción Pérez-Jorge, Teresa Cabezas-Fernández, Daniel Blázquez-Gamero, Gonzalo Rivas, Patricia Gonzalez-Donapetry, Elena Sáez, Jovita Fernández-Pinero, Jesús Lucas-Fernández, Elisa Pérez-Ramírez, Paloma Merino, Sandra Miragaya, Jorge Lorente, Irene Iglesias, Alfredo Tagarro

    The results from this multi-centre prospective diagnostic test accuracy study suggest that molecular testing of oral saliva samples for SARS-CoV-2 in children is an accurate and less invasive alternative to molecular testing of nasopharyngeal/oropharyngeal swabs.