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Images in paediatrics
An unusual presentation of giant juvenile xanthogranuloma in a 9-year-old child
  1. Molly Papadopoullos1,
  2. Lucy Smith2,
  3. Muhammad Aslam3,
  4. Periasamy Balasubramaniam2
  1. 1 School of Medicine, Cardiff University, Cardiff, UK
  2. 2 Department of Dermatology, Betsi Cadwaladr University Health Board, North Wales, UK
  3. 3 Department of Histopathology, Betsi Cadwaladr University Health Board, North Wales, UK
  1. Correspondence to Dr Lucy Smith, Dermatology, Wrexham Maelor Hospital, Wrexham, UK; lucyelizabethsmith{at}

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A previously healthy 9-year-old boy presented to dermatology outpatient clinic with a 2-month history of an enlarging nodule on the anterior right shoulder (figure 1). There were no specific symptoms, family history or relevant medical history. Examination demonstrated a 1×1 cm indurated yellow nodule with ulceration. Differential diagnoses included giant molluscum, giant juvenile xanthogranuloma (JXG) and keratoacanthoma. Histology from an incisional biopsy demonstrated surface excoriation and focal erosion with underlying dense monomorphous histiocytic population with …

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  • Contributors MP was responsible for writing the primary article. LS was significantly involved in editing the article, obtaining parental consent and coordinating the overall project. PB was the consultant leading this child’s care and supervised the project. AM provided the histopathological report and images.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Competing interests None declared.

  • Provenance and peer review Not commissioned; internally peer reviewed.