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Contributors DW conceived the paper and wrote first draft. DW and ACM reviewed and revised paper and approved the final version for submission.
Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.
Competing interests DW is Chair of the Expert advisory Group to NHS England and was Principal Investigator for the MRC-funded Child-parent Screening Study.
Provenance and peer review Commissioned; internally peer reviewed.
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