Table of contents

December 2021 - Volume 106 - 12





Clinical law for clinical practice

Global child health

  • Oxygen saturation reference ranges and factors affecting SpO2 among children living at altitude
    (24 May, 2021) Free
    Vanessa Binene, Doreen Panauwe, Rhondi Kauna, John D Vince, Trevor Duke

    This study of children living at 2600m in Papua New Guinea identified risks for lower saturations within the overall population. Saturations were lower in certain groups within the well population of infants and children, pointing to vulnerabilities not previously recognized.

  • Epidemiology, clinical features and outcomes of incident tuberculosis in children in Canada in 2013–2016: results of a national surveillance study (20 August, 2021) Free
    Shaun K Morris, Ryan J P Giroux, Raquel Consunji-Araneta, Kristoffor Stewart, Maureen Baikie, Fatima Kakkar, David Zielinski, Alena Tse-Chang, Victoria J Cook, Dina A Fisher, Marina I Salvadori, Jeffrey M Pernica, Laura J Sauve, Charles Hui, Amber Miners, Gonzalo G Alvarez, Assaad Al-Azem, Victor Gallant, Barbara Grueger, Ray Lam, Joanne M Langley, Nicole Radziminski, Elizabeth Rea, Sam Wong, Ian Kitai

    Information gleaned from a national surveillance network in Canada which identified 200 cases of childhood tuberculosis over three years finds that indigenous children are disproportionately infected.

Paediatric emergency medicine

Original research

  • Improved renal allograft survival for pre-emptive paediatric renal transplant recipients in the UK (20 May, 2021)
    Matko Marlais, Kate Martin, Stephen D Marks

    The debate about the benefit of pre-emptive kidney transplantation in paediatric patients gets support by recent data from the UK Transplant Registry. Five years graft survival rate was significantly better in pre-emptive transplantation, and dialysis's time negatively impacted.

  • Experiences of adolescents living with Silver-Russell syndromeEditor's Choice (19 March, 2021) Free
    Lisa Marie Ballard, Elizabeth Jenkinson, Christopher D Byrne, Jenny C Child, Hazel Inskip, Oluwakemi Lokulo-Sodipe, Deborah J G Mackay, Emma L Wakeling, Justin Huw Davies, I Karen Temple, Angela Fenwick

    In depth qualitative interviews with young people growing up with Silver- Russell syndrome identified multiple psychosocial challenges. Currently young people are discharged and not monitored into adulthood. This may need to change

  • Intrathecal baclofen pumps in the management of hypertonia in childhood: a UK and Ireland wide survey (14 April, 2021)
    Rajib Lodh, Sam Amin, Amr Ammar, Lucy Bellis, Phillip Brink, Amedeo Calisto, Darach Crimmins, Paul Eunson, Rob J Forsyth, John Goodden, Margaret Kaminska, Joanne Kehoe, Martin Kirkpatrick, Ram Kumar, Jane Leonard, Alice Lording, Katherine Martin, Russell Miller, Santosh R Mordekar, Benedetta Pettorini, Martin Smith, Rachel Smith, Christine Sneade, Andrea Whitney, Michael Vloeberghs, Hesham Zaki, Daniel E Lumsden

    All twelve centres in Great Britain and Ireland that provide intrathecal baclofen therapy report results over a 5 month period. There is considerable variation in referral criteria and the way it is used. There is a need for greater standardisation of ITB therapy to ensure equality of provision.

  • Listeria infection in young infants: results from a national surveillance study in the UK and Ireland (13 May, 2021)
    Stefania Vergnano, Gauri Godbole, Ameze Simbo, Alison Smith-Palmer, Martin Cormican, Mark Anthony, Paul T Heath

    Who needs empirical treatment for Listeria infection? This national surveillance study found that invasive listeriosis in young infants in the UK and Ireland is rare and presented only in the neonatal period. Use of amoxicillin as part of empiric treatment for sepsis and meningitis in infants over 1 month of age may be unnecessary.


Short report

  • Delivering tertiary tuberculosis care virtually (22 June, 2021)
    Louise Turnbull, Christine Bell, Stefanie Davies, Fran Child

    A weekly virtual clinic with MDT discussion between between district paediatricians and a tertiary TB team showed that:45% children received care closer to home. Median time from presentation to treatment reduced by 28%. 21% more children diagnosed before developing symptoms.




Electronic pages