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A 3-year-old girl presented with recurrent multiple painful ulcerative lesions for 10 months. The ulcer on the forehead rapidly progressed and involved both cheeks and nose with yellowish purulent discharge in recent 20 days (figure 1A). She was treated with antibiotics resulting in no response. She had no systemic, gastrointestinal and arthritic symptoms. Laboratory examination found elevated white blood cell (39.72×109/L) and decreased haemoglobin (77 g/L). Bone …
Contributors JC and HW wrote the manuscript in consultation with FR.
Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.
Competing interests None declared.
Provenance and peer review Not commissioned; externally peer reviewed.