How much of a good thing do we need?

Not-sure-ness … There could be a variety of answers to the title drawn from the repertoire of popular music, ranging from a dusting to a life embodied. In the setting of evidence-based medicine … like almost every question that’s asked … the answer is probably ‘It depends’.

If our question regards the use of a significantly toxic or complex therapy, where other options exist, I’d be wanting a fair …