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Contributors BR and EC conceived and designed the study. BR drafted the manuscript with support from JW, JO, NRS and EC. All authors provided critical feedback on the manuscript and analysis. All authors approved the final manuscript.
Funding Eyal Cohen is supported by the Canadian Institutes of Health Research (FDN-143315). The opinions in this article are those of the authors and independent from all funding sources.
Competing interests None declared.
Patient consent for publication Not required.
Provenance and peer review Not commissioned; externally peer reviewed.
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