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Co-trimoxazole prophylaxis may not be necessary in breast feeding HIV-exposed, HIV-uninfected infants

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The treatment for HIV infected mothers and their children has advanced markedly over the last decade. There are a number of recommendations from the WHO concerning the treatment and management for the breast feeding HIV-exposed, HIV-uninfected infants. Suggestions are to commence co-trimoxazole in these infants from age 6 weeks until breastfeeding has stopped and the infants are confirmed not to be infected with HIV. There are now effective prevention of mother-to-child transmission and early infant diagnosis programmes. Are there data to support this approach? Daniels B et al . [Lancet Global Health 2019 https://doi.org/10.1016/S2214-109X(19)30422-X] …

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