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Original article
Adherence to metformin is reduced during school holidays and weekends in children with type 1 diabetes participating in a randomised controlled trial
  1. Catherine Leggett1,
  2. Lynne Giles2,
  3. Jemma Jay Angela Anderson3,4,
  4. Matthew Doogue5,
  5. Jennifer Couper3,4,
  6. Alexia Sophie Pena3,4
  1. 1 SA Pharmacy, Women’s and Children’s Hospital, North Adelaide, South Australia, Australia
  2. 2 School of Public Health, University of Adelaide, Robinson Institute, Adelaide, South Australia, Australia
  3. 3 Endocrinology and Diabetes Department, Women’s and Children’s Hospital, North Adelaide, South Australia, Australia
  4. 4 Discipline of Paediatrics, University of Adelaide, Robinson Research Institute, Adelaide, South Australia, Australia
  5. 5 Department of Medicine, University of Otago, Christchurch, New Zealand
  1. Correspondence to Catherine Leggett, SA Pharmacy, Women’s and Children’s Hospital, North Adelaide, South Australia 5006, Australia; catherine.leggett{at}sa.gov.au

Footnotes

  • Contributors CL drafted the manuscript and had full access to the study data and acquired, analysed and interpreted the data and takes responsibility for the integrity of the contents of the article, the data and the accuracy of the data analysis. LG drafted the manuscript, provided statistical analysis and had full access to all of the data in the study and take responsibility for the integrity of the contents of the article, the data and the accuracy of the data analysis. JJAA obtained funding for this study and had full access to the study data and acquired, analysed and interpreted the data and takes responsibility for the integrity of the contents of the article, the data and the accuracy of the data analysis. MD drafted the manuscript and acquired, analysed and interpreted the data. ASP and JC obtained funding for this study, drafted the manuscript and had full access to the study data and acquired, analysed and interpreted the data and take responsibility for the integrity of the contents of the article, the data and the accuracy of the data analysis. All authors critically reviewed the manuscript for important intellectual content and approved the final version for publication.

  • Funding This study was funded by Diabetes Australia Research Trust, Women’s and Children’s Foundation research project grants and Australasian Paediatric Endocrine Care grants. JJAA held an MS McLeod Research Foundation fellowship.

  • Disclaimer The funders had no role in the design and conduct of the study; collection, management, analysis and interpretation of the data; preparation, review or approval of the manuscript; and decision to submit the manuscript for publication.

  • Competing interests None declared.

  • Ethics approval The trial was approved by the Women’s and Children’s Hospital Research Ethics Committee (HREC 2327/12/13) and Flinders Medical Centre Research Ethics Committee (HREC 443.12).

  • Provenance and peer review Not commissioned; externally peer reviewed.

  • Patient consent for publication Not required.

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Footnotes

  • Contributors CL drafted the manuscript and had full access to the study data and acquired, analysed and interpreted the data and takes responsibility for the integrity of the contents of the article, the data and the accuracy of the data analysis. LG drafted the manuscript, provided statistical analysis and had full access to all of the data in the study and take responsibility for the integrity of the contents of the article, the data and the accuracy of the data analysis. JJAA obtained funding for this study and had full access to the study data and acquired, analysed and interpreted the data and takes responsibility for the integrity of the contents of the article, the data and the accuracy of the data analysis. MD drafted the manuscript and acquired, analysed and interpreted the data. ASP and JC obtained funding for this study, drafted the manuscript and had full access to the study data and acquired, analysed and interpreted the data and take responsibility for the integrity of the contents of the article, the data and the accuracy of the data analysis. All authors critically reviewed the manuscript for important intellectual content and approved the final version for publication.

  • Funding This study was funded by Diabetes Australia Research Trust, Women’s and Children’s Foundation research project grants and Australasian Paediatric Endocrine Care grants. JJAA held an MS McLeod Research Foundation fellowship.

  • Disclaimer The funders had no role in the design and conduct of the study; collection, management, analysis and interpretation of the data; preparation, review or approval of the manuscript; and decision to submit the manuscript for publication.

  • Competing interests None declared.

  • Ethics approval The trial was approved by the Women’s and Children’s Hospital Research Ethics Committee (HREC 2327/12/13) and Flinders Medical Centre Research Ethics Committee (HREC 443.12).

  • Provenance and peer review Not commissioned; externally peer reviewed.

  • Patient consent for publication Not required.

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