Article Text

Download PDFPDF
Highlights from the literature

Statistics from

Request Permissions

If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.

Brief Resolved Unexplained Events and Gastro-oesophageal reflux

It is very easy to start treatment for presumed gastro-oesophageal reflux (GOR) in a well infant who has presented with a Brief Resolved Unexplained Event (BRUE) which has been classified as low risk. Lucina has never been convinced that gastro-oesophageal reflux is a major cause for BRUEs or what used to be known as an Apparently Life Threatening Event (ALTEs) until 2016 [Pediatrics 2016;137 (5):e20160590]. Duncan et al. [J Pediatrics 2019] have examined a retrospective cohort of infants from Bostons’ Childrens hospital who had been diagnosed with BRUE as per the American Academy of Paediatrics guidelines. They looked 1 year before and 1 year after guideline implementation to determine if practice patterns have changed. They looked at 359 subjects (186 pre-, 173 post-guidelines). There were no significant differences in practice patterns or outcomes before or after guideline implementation. Each subject had over two diagnostic tests performed, and 89% were noncontributory. Interestingly, 13% had a videofluoroscopic swallow study performed, and 72% showed aspiration/penetration. No subject had gastro-oesophageal reflux testing, yet reflux was …

View Full Text


  • Provenance and peer review Commissioned; internally peer reviewed.