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G309(P) Predictive value of electroencephalography for developmental outcome at 6 month of age in full term neonates with seizures
  1. M Ramwani,
  2. A Singh,
  3. J Shrivastava,
  4. A Agarwal
  1. Department of Paediatrics, Gandhi Medical College, Bhopal, India

Abstract

Background Electroencephalography (EEG) is an important tool to evaluate infant with symptoms refer to central nervous system. The objective of the work was to study the predictive value of EEG for developmental outcome in full term neonates with seizures at 6 month of age.

Methods This was prospective observational study at tertiary care centre, Gandhi Medical College, Bhopal. The participants were full term hospitalised neonates with documented seizures. Newborns admitted for complaints other than seizures, hypoxic ischaemic encephalopathy (HIE) stage 1, preterm and neonates born to mother on antiepileptic therapy were excluded from the study.

Results Out of total 108 registered neonates 14 expired and 10 lost to follow up. In remaining 84 cases, 36 (42.9%) had generalised discharge, 16 (19%) had focal and 6 (7.1%) had multifocal discharge while 44 (52.3%) had normal EEG patterns. HIE being the most common cause and subtle seizure being the most common type of seizures. On follow up at 6 month, all neonates with normal EEG pattern (n=44) had normal developmental outcome. Out of 40 neonates with abnormal EEG discharges, 26 (65%) had developmental delay, while 14 (35%) had normal development for age.

Conclusions EEG could be a simple and cost effective prognostic tool where neonates presenting with seizure. Newborn with abnormal discharge should be closely monitored on DDST for early identification and early intervention.

  • Electroencephalography
  • Outcome
  • Seizures
  • DDST

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