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Adenovirus infection: beware of plasma procalcitonin levels in children
  1. Vanessa Laveglia,
  2. Nuria Gorina,
  3. Pia Cassanello
  1. Department of Pediatrics, Hospital Universitari General de Catalunya, Barcelona, Spain
  1. Correspondence to Dr Vanessa Laveglia, Department of Pediatrics, Hospital Universitari General de Catalunya, Barcelona 08190, Spain; vanessalaveglia{at}

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We have carefully read the report by Elenius et al.1 They suggested that low procalcitonin (PCT) levels in adenovirus (ADV) infections could be used as a marker for withholding antibiotic therapy.

It is well established that white blood cell (WBC) counts and serum C reactive protein (CRP) are usually high in these infections and that PCT should perform better in differentiating between ADV and bacterial infections.2 We reviewed our experience to analyse whether PCT levels impacted on antibiotic prescribing. We conducted a retrospective study in our tertiary care paediatric unit. Clinical and laboratory data were …

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  • Contributors VL designed the study. All authors wrote the manuscript. PC and VL analysed the data.

  • Competing interests None declared.

  • Provenance and peer review Not commissioned; internally peer reviewed.