Statistics from Altmetric.com
The importance of prompt resuscitation with intravenous (IV) fluids in children with presumed sepsis or severe dehydration is well-known, and is emphasised in all resuscitation guidelines. But have we gone too far? The FEAST trial published in 2011 set alarm bells ringing (doi: 10.1056/NEJMoa1101549). In a sub-Saharan Africa setting, it showed that very ill, febrile children randomised to fluid boluses of either saline or albumin had a 3.3% higher mortality than those receiving only maintenance fluids. Those with gastro-enteritis were excluded. Since then questions have been asked about whether we might also be doing harm to less ill children in Western settings by overuse of fluids. …
Competing interests None declared.
Provenance and peer review Commissioned; internally peer reviewed.
If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.