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Images in paediatrics
Cutaneous Langerhans cell histiocytosis presenting in a neonate
  1. Katherine J Pettinger1,
  2. Lea Solman2,
  3. Bipin Mathew3,
  4. Gayle Taylor2,
  5. Sheila Clark2,
  6. Susan Picton4
  1. 1 Neonatal Unit, Leeds General Infirmary, Leeds, UK
  2. 2 Department of Dermatology, Chapel Allerton Hospital, Leeds, UK
  3. 3 Department of Cellular Pathology, St James’s Hospital, Leeds, UK
  4. 4 Department of Paediatric Oncology and Haematology, Leeds General Infirmary, Leeds, UK
  1. Correspondence to Dr Katherine J Pettinger, Neonatal Unit, Leeds General Infirmary, Great George Street, Leeds, LS1 3EX, UK; katherine.pettinger{at}

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A newborn boy presented at birth with a firm erythematous nodule, measuring 25×18 mm on the medial aspect of his left shin below the knee (figure 1). The lesion had a depressed centre covered with a crust and subtle telangiectasia on the edges. The rest of the examination was normal. He had been born at term following an uncomplicated pregnancy.

Figure 1

Erythematous nodule measuring 25×18 mm on the medial aspect left shin.

A 4 mm punch biopsy of the lesion was performed, revealing S100 and …

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  • Contributors KP wrote the case report. LS carried out the literature review. BM produced the figure panel (fig. 2) and wrote the corresponding caption. GT, SC and SP reviewed the work.

  • Competing interests None declared.

  • Patient consent Parental consent obtained.

  • Provenance and peer review Not commissioned; externally peer reviewed.

  • Presented at A version of this case was presented as a poster at the European Society for Pediatric Dermatology annual meeting, and the abstract was published in an abstract book: Solman, L, Pettinger, K, Taylor, G, et al. P118. Pediatr Dermatol 2017;34:S19–S56. doi:10.1111/pde.13268.