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Letter
Hypertension outcomes and cardiovascular status in young adults with childhood-diagnosed white coat hypertension
  1. Maria Westerståhl1,2,
  2. Maria Forss3,
  3. Lena Persson1,
  4. Karin Bouma1,
  5. Thomas Gustavsson2,
  6. Elke Wühl4,
  7. Rafael T Krmar5
  1. 1 Department of Laboratory Medicine, Clinical Physiology, Karolinska Institutet, Stockholm, Sweden
  2. 2 Unit of Clinical Physiology, Karolinska University Hospital, Huddinge, Sweden
  3. 3 Division of Pediatrics, Karolinska University Hospital, Stockholm, Sweden
  4. 4 Center for Pediatrics and Adolescent Medicine, University of Heidelberg, Heidelberg, Germany
  5. 5 Department of Physiology and Pharmacology (FYFA), Karolinska Inst, Stockholm, Sweden
  1. Correspondence to Dr Rafael T Krmar, Department of Physiology and Pharmacology (FYFA), Karolinska Institutet, C3, Nanna Svartz Väg 2, Stockholm S-171 77, Sweden; rafael.krmar{at}ki.se

https://doi.org/10.1136/archdischild-2017-313298

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    White coat hypertension (WCH) describes untreated subjects displaying elevated blood pressure (BP) in the clinical setting as opposed to normal ambulatory BP monitoring (ABPM) or BP taken at home.1 Adults with WCH are more likely to progress to sustained hypertension (SH) and to be at increased cardiovascular risk compared with normotensive subjects.2 Since it is unknown whether children with WCH progress to SH,3 we sought to determine hypertension outcomes using ABPM and cardiovascular status in young adults with childhood-diagnosed WCH.

    In a previous study conducted in Swedish healthy schoolchildren, we identified 56 (3.8%) out of 1470 participants as having WCH, which was defined as systolic and/or diastolic casual BP >95th distribution adjusted height-related and sex-related percentile in three separate visits, but …

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    Footnotes

    • Contributors RTK has full access to all the data in the study and takes responsibility for the integrity and the accuracy of the data analysis. Study concept and design: RTK. Acquisition, analysis or interpretation of the data: All authors. Statistical analysis: MW, EW and RTK. Drafting of the letter: RTK. Critical revision of the manuscript for important intellectual content: All authors.

    • Competing interests None declared.

    • Patient consent Obtained.

    • Ethics approval Regional Ethical Review Board Stockholm (www.epn.se).

    • Provenance and peer review Not commissioned; externally peer reviewed.

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