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P153 Height≥85 percentile with increased body mass index (BMI) is risk factor for cardio-vascular diseases height≥85 percentile with increased body mass index (BMI) is risk factor for cardio-vascular diseases
  1. Olga Kozhevnikova,
  2. Leyla Namazova-Baranova,
  3. Eka Abashidze,
  4. Vlad Lebedev,
  5. Elena Antonova,
  6. Olga Logacheva,
  7. Anna Batyrova,
  8. Irina Shirokova.
  1. FSAI «National Research and Practical Centre of Children’s Health» of the Ministry of Health of Russia, Moscow, Russia


Background It was marked that children with increased BMI have high height due to insulin resistance or elevating insulin/IGF1. The Insulin resistant can be reason of cardio-vascular diseases.

Aim to find the early detection of risk factors for cardiovascular diseases in children with height≥85 percentile age-sex norm

Methods 854 children aged 3–17 y.o. were examined (included 87 with height≥85 percentile): by arterial stiffness device (TensioMed,Hungary) – 211; by 24 hour monitoring of ECG and blood pressure(Astrocard, Russia) – 92; by Polysomnography (Embla-S7000,USA)- 45; by system of continuous glucose monitoring (Guardian, USA) – 14 children.

Results Children with increased BMI and with height≥85 percentile in comparison with middle height had a significantly lower augmentation index, in 5 times more often – decreased diastolic blood pressure at night, lower level of high density lipoproteids; if they had obesity- the normal 24 hour dynamics of blood pressure was disappeared, if they had overweight- there was more longer QT interval at night, if they had sleep obstructive apnea-hypopnea syndrom there were some periods of glycemia less then 3.3 mmol/L at night.

Conclusions Children with height≥85 percentile of age- and gender-based norms with increased BMI and, especially, with nasal obstruction have an additional risk of cardio-vascular diseases.

Disclosure of Interest None Declared

  • cardiovascular risk factors
  • BMI
  • arteriography
  • polysomnography
  • obesity
  • blood pressure

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