Aim To audit the management of neonatal sepsis and to introduce measures to improve its identification and management in a low resource-setting, both among hospital staff and in the wider community.

Method A multi-cycle audit was conducted with performance measured against ETAT+ guidelines. Neonatal sepsis admissions were audited on 3 occasions; pre-intervention, at 3 months and 6 months, with multiple interventions continuing throughout this tim

Interventions included:

• Hospital wide teaching to all cadre staff based on ETAT+ principles.

• Outreach teaching to referring centres

• Delivery of a daily standardised health talk and the provision of parental leaflet to post-natal mothers.

• Demonstration of health promotion videos

• Posters displayed in hospital and community dispensaries.

• Local staff engaged and motivated by clinical feedback and presentation of audit results.

Results 126 patients were audited. Results demonstrate sustained improvement in important parameters

Conclusion A multi-strategy approach is successful in showing a sustained improvement to the management of neonatal sepsis in a low resource setting