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A child aged 7 years is being discharged home on oral immunosuppressants following a renal transplant. You routinely advise children in this situation to avoid foods such as unpasteurised cheeses and fresh pastries. You wonder whether this low-bacterial diet will actually prevent infection.
Structured clinical question
In a child on immunosuppressive therapy (patient), does adherence to a low-bacterial diet (intervention) compared with normal, unrestricted diet (control) lead to reduced incidence of infection (outcome) and whether these dietary restrictions lead to reduced quality of life and/or are acceptable to the patients (secondary outcomes)?
Search date 26 September 2016
We searched the Cochrane library, PubMed, Web of Science, Scopus, Embase/OVID and CINAHL for the following terms: (‘low bacterial diet’ OR ‘low bacteria diet’ OR ‘low microbial diet’) AND (immunosuppres* OR neutropeni*)
AND (sepsis OR infection). We found 30 individual articles (77 including duplicates), of which …
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Contributors AJF carried out the literature search. AJF and SM reviewed the results and decided on papers to be included/excluded. AJF wrote the manuscript which was then reviewed by SM.
Competing interests None declared.
Provenance and peer review Not commissioned; externally peer reviewed.