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Post-exposure prophylaxis guidelines for children and adolescents potentially exposed to HIV
  1. Alasdair Bamford1,
  2. Gareth Tudor-Williams2,
  3. Caroline Foster2
  1. 1Department of Paediatric Infectious Diseases, Great Ormond Street Hospital for Children NHS Trust, London, UK
  2. 2Department of Paediatric Infectious Diseases, St Mary's Hospital, Imperial College Healthcare NHS Trust, London, UK
  1. Correspondence to Dr Caroline Foster, Department of Paediatric Infectious Diseases, St Mary's Hospital, Imperial College Healthcare NHS Trust, Praed Street, London W2 1NY, UK; caroline.foster{at}


UK guidelines for HIV post-exposure prophylaxis (PEP) in adults have recently been updated. Indications for PEP have been modified and there has been a change in the recommended antiretroviral therapy for adults to a combination of raltegravir with tenofovir and emtricitabine (Truvada). Raltegravir and tenofovir are now available in paediatric formulations and offer improved safety and tolerability over previously recommended ritonavir-boosted lopinavir with zidovudine. This guideline provides recommendations for those caring for children potentially exposed to HIV and other bloodborne viruses in primary care, emergency departments, secondary care and specialist paediatric HIV centres.

  • HIV
  • Children
  • Prophylaxis
  • Guideline
  • Post exposure

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  • Contributors CF, GT-W and AB proposed, composed and reviewed the guideline. AB performed the literature review and formatted the guideline for submission. AB, GT-W and CF approved the final version for submission.

  • Competing interests None declared.

  • Provenance and peer review Commissioned; externally peer reviewed.