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Managing the child with a diagnosis of Moebius syndrome: more than meets the eye


Moebius syndrome (MBS) is a congenital, non-progressive facial and abducens nerve palsy in the presence of full vertical gaze and may be associated with limb abnormalities and craniofacial dysmorphisms. MBS is now defined as a disorder of rhombencephalic maldevelopment and recent gene discoveries have shown this to be a dominant disorder in a subset of patients. Accurate diagnosis and management by a multidisciplinary team with expertise in congenital facial palsy is paramount.

  • Moebius syndrome
  • Möbius sequence
  • management
  • minimum diagnostic criteria
  • rhombencephalic maldevelopment

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