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Serious infection affects around 20% of patients who present febrile and neutropenic.1 Febrile neutropenia (FN) is thus a well-recognised medical emergency. Addressing the challenges of both rapid delivery of antibiotics to patients at risk of life-threatening sepsis and appropriate antibiotic stewardship to reduce antibiotic overuse continues to keep this a priority for clinicians, patients and parents. Audits of FN practice have previously demonstrated variation in definitions for FN and its management.1 ,2 In September 2012, the National Institute for Health and Care Excellence (NICE) published the ‘Neutropenic sepsis: prevention and management of neutropenic sepsis in cancer patients’3 guideline and we sought to assess if this has reduced variations in practice.
This reaudit included 45 UK centres (14 …
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Contributors The study was designed by BP, JB, EJ and JC. Data analysis and initial report writing were performed by FH with significant editing and review by BP and JB. EJ and JC reviewed the final manuscript.
Competing interests None declared.
Provenance and peer review Not commissioned; internally peer reviewed.
Data sharing statement Further data are available on the CCLG website and centres received centre-specific data on their management of patients over the 2-week period and how these compare with guidelines and overall performance.