Article Text

Download PDFPDF
Lack of effect of azithromycin on QT interval in children: a cohort study
  1. David Espadas,
  2. Silvia Castillo,
  3. Marcela Moreno,
  4. Amparo Escribano
  1. Pediatric Pulmonology Unit, University Clinical Hospital of Valencia, University of Valencia, Valencia, Spain
  1. Correspondence to Professor Amparo Escribano, Unidad de Neumología Infantil, Hospital Clínico Universitario de Valencia. Av. Blasco Ibáñez, 17., Valencia 46010, España; aescribano{at}

Statistics from

Request Permissions

If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.

Macrolides are a group of antimicrobial drugs used widely, being well known for their adverse cardiac effects. Erythromycin and clarithromycin are most commonly associated with these conditions. In recent years, azithromycin (AZM) has been assessed because of its possible relation to arrhythmias (mainly QT interval prolongation) and risk of cardiovascular death.1 The pharmacodynamics of these effects is complex and the occurrence of cardiovascular death is unpredictable.2 However, all published manuscripts on the cardiac effects of AZM to date are cases in adults or …

View Full Text


  • Competing interests None declared.

  • Patient consent Parental/guardian consent obtained.

  • Provenance and peer review Not commissioned; externally peer reviewed.