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G144(P) Hypoxic ischaemic encepahlopathy in transport: how has the introduction of cooling and end tidal co2 monitoring affected our patients?
  1. J Williams,
  2. J Spencer,
  3. A Fenton
  1. Neonatal Intensive Care Unit, Royal Victoria Infirmary, Newcastle-Upon-Tyne, UK


Background Hypoxic Ischaemic Encephalopathy (HIE) occurs in 1/500 babies and can lead to cerebral palsy. Treatment focuses on preventing secondary brain injury. Early cooling and strict CO2 control may have a positive effect on neurodevelopmental outcome. Optimal management of babies born outside of tertiary units during retrieval could improve their outcome.

Method Single centre cohort study of referrals for tertiary care with HIE 1996–2013. Using the transport database and retrieval documentation we reviewed CO2 on departure from the referring unit and arrival at the tertiary unit before and after the introduction of end tidal CO2 (ETCO2) monitoring. We also reviewed temperature on departure and arrival before and after the introduction of cooling as a recognised treatment modality. We ask whether distance travelled affects data.

Results There were 148 referrals for transfer. 52/148 were referred after introduction of cooling. 35% were at the desired temperature (33–34 degrees) at departure from referring unit increasing to 40% on arrival at the tertiary unit. 21/148 were referred after the introduction of ETCO2 monitoring. Before the introduction of ETCO2 25% of babies had a CO2 in the desired range (5–7 kPa) at departure increasing to 33% on arrival (not all babies had values documented). Following the introduction of ETCO2 25% of babies had a CO2 in the desired range at departure rising to 50% on arrival. Travelling a shorter distance did not inevitably lead to a decreased ability to alter temperature or CO2 in transit. There was a slight tendancy to over-ventilate and babies were more likely to be above the desired temperature during transport.

Conclusion Some units are further away from the tertiary centre. Although cooling as an entity has been adopted by peripheral units there is potential for more aggressive targeting of desired temperature before the transport team arrives and during transfer. ETCO2 allows us to manage CO2 better but there is room to be more targeted both by the referring unit and also in transport. The effect cooling equipment in transport would have on our data is yet to be addressed.

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