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Images in paediatrics
Severe combined immunodeficiency syndrome presenting with disseminated BCG infection
  1. Patrick Fitzpatrick1,
  2. Jane Leonard1,
  3. Eilis Twomey1,
  4. Andrea Malone1,
  5. Zohreh Nademi2,
  6. Michael Jackson3,
  7. Mario Abinun2,
  8. Timothy Ronan Leahy1,
  9. Patrick J Gavin1
  1. 1Children's University Hospital, Dublin, Ireland
  2. 2Newcastle upon Tyne Hospital Trust, Newcastle, UK
  3. 3Great North Children's Hospital, Newcastle, UK
  1. Correspondence to Patrick Fitzpatrick;

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A 4-month-old boy presented with fever, lethargy and irritability on a background of faltering growth. He was pale, febrile, in respiratory distress. He had red papular skin lesions on torso and a large discharging ulcer at BCG inoculation site (administered shortly after birth) (figure 1).

Figure 1

BCG inoculation site on left upper arm.

He was anaemic (haemoglobin 4.8 g/dL) and lymphopenic (1.16×109/L) …

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  • Contributors PF and PJG conceived case report. PF prepared first draft of manuscript, and co-ordinated and edited contributions of other authors. All other authors provided contributions and revisions, and approved the final draft of the manuscript. TRL and PJG also provided senior supervision.

  • Competing interests None declared.

  • Patient consent Obtained.

  • Provenance and peer review Not commissioned; externally peer reviewed.