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Towards evidence based medicine for paediatricians
  1. Bob Phillips
  1. Correspondence to Dr Bob Phillips, Centre for Reviews and Dissemination, University of York, York YO10 5DD, UK; bob.phillips{at}doctors.org.uk

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I-squared

No, not −1, the self-multiplication of that fancy imaginary number that helps aircraft designers make wings work properly, but a (semi) quantitative assessment of how much heterogeneity there is in a meta-analysis: I2.

You will recall that the idea of heterogeneity (mixed-up-ness) comes in both statistical and clinical flavours.1 This measure—(I2)—assesses the statistical aspect. It is often to be found …

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