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We read with interest the letter by Dr Krasseman1 regarding anti-inflammatory doses of aspirin used in the acute phase of Kawasaki disease (KD). Indeed, higher doses of aspirin are currently used in the USA (80–100 mg/kg/day), while in Japan a lower dose of 30–50 mg/kg/day is advocated.2–6 Similarly, in the UK, the latter modest dose has been recommended since 20027 ,8 for the acute phase of KD as a number of previous studies have suggested this lower dose is equally as effective, and may be associated with less toxicity.2 ,4 …
Competing interests None.
Provenance and peer review Not commissioned; internally peer reviewed.
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