Introduction Hodgkin lymphoma is malignant disease of cells in the lymphatic system that is characterized by proliferation of Reed - Sternberg cells. Symptoms include the painless swelling of lymph nodes, spleen, or other immune tissue. Other symptoms include fever, weight loss, fatigue, or night sweats. Also called Hodgkin disease.

Objective Was the presentation a case with Hodgkin lymphoma, treated in Pediatric Clinic in Prishtina at the Hemato-Oncology Unit.

Methods Patient, male child, 9 years old, came in the clinic because of painless enlargement of lymph nodes on the left side of the neck. Other examinations, according to systems have been in normal range. Diagnosis is made based on anamnesis, clinical examination, laboratory, ultrasound, CT, histopathology with immunochemistry, and bone marrow aspiration. The surgery has been made and according to path-histological and immunochemistry analyses the diseases has been diagnosed as Type - Classic of Hodgkin lymphoma (mixed celularity).

Results The treatment is done according to protocol for Hodgkin lymphona, with three cycles of OEPA (Prednisone, Vincristine, Doxorubicine, Etoposide), and three cycles of COPP (Prednisone, Procarbazine, Vincristine, Cyclophosphamide).After therapy, the PET - scan has been made and its results show that nowhere in the body is present malignant infiltration.

Conclusion OEPA and COPP are very efficient therapy in the treatment of Hodgkin lymphoma.