Managing bone and joint infection in children

SN Faust, J Clark, A Pallett, NMP Clarke - Archives of disease in …, 2012 - adc.bmj.com
There is little high quality evidence on which to base the management of bone and joint
infections in children. This pragmatic practice note aims to provide a consensus framework …

Association between the abnormal expression of matrix‐degrading enzymes by human osteoarthritic chondrocytes and demethylation of specific CpG sites in the …

HI Roach, N Yamada, KSC Cheung… - … : Official Journal of …, 2005 - Wiley Online Library
Objective To investigate whether the abnormal expression of matrix metalloproteinases
(MMPs) 3, 9, and 13 and ADAMTS‐4 by human osteoarthritic (OA) chondrocytes is …

The effect of the delivery of vascular endothelial growth factor and bone morphogenic protein-2 to osteoprogenitor cell populations on bone formation

JM Kanczler, PJ Ginty, L White, NMP Clarke… - Biomaterials, 2010 - Elsevier
Regenerating bone tissue involves complex, temporal and coordinated signal cascades of
which bone morphogenic protein-2 (BMP-2) and vascular endothelial growth factor …

Acute haematogenous osteomyelitis in children: is there any evidence for how long we should treat?

S Weichert, M Sharland, NMP Clarke… - Current opinion in …, 2008 - journals.lww.com
Acute haematogenous osteomyelitis in children: is there any... : Current Opinion in Infectious
Diseases Acute haematogenous osteomyelitis in children: is there any evidence for how long …

A review of environmental factors implicated in human developmental dysplasia of the hip

AML Rhodes, NMP Clarke - Journal of children's …, 2014 - journals.sagepub.com
Purpose Developmental dysplasia of the hip (DDH) is common, and the term encompasses
a spectrum of anatomical abnormalities of the hip in which the femoral head displaces from …

Temporal analysis of rat growth plates: cessation of growth with age despite presence of a physis

HI Roach, G Mehta, ROC Oreffo… - … of Histochemistry & …, 2003 - journals.sagepub.com
Despite the continued presence of growth plates in aged rats, longitudinal growth no longer
occurs. The aims of this study were to understand the reasons for the cessation of growth …

[HTML][HTML] Reliability of a new radiographic classification for developmental dysplasia of the hip

U Narayanan, K Mulpuri, WN Sankar… - Journal of Pediatric …, 2015 - journals.lww.com
Background: Existing radiographic classification schemes (eg, Tönnis criteria) for DDH
quantify the severity of disease based on the position of the ossific nucleus relative to …

Displaced supracondylar fractures of the humerus in children: audit changes practice

LJ O'hara, JW Barlow… - The Journal of Bone & Joint …, 2000 - boneandjoint.org.uk
We performed an audit of 71 children with consecutive displaced, extension-type
supracondylar fractures of the humerus over a period of 30 months. The fractures were …

The effect of mesenchymal populations and vascular endothelial growth factor delivered from biodegradable polymer scaffolds on bone formation

JM Kanczler, PJ Ginty, JJA Barry, NMP Clarke… - Biomaterials, 2008 - Elsevier
The capacity to deliver, temporally, bioactive growth factors in combination with appropriate
progenitor and stem cells to sites of tissue regeneration promoting angiogenesis and …

Induction of human osteoprogenitor chemotaxis, proliferation, differentiation, and bone formation by osteoblast stimulating factor‐1/pleiotrophin: Osteoconductive …

X Yang, RS Tare, KA Partridge, HI Roach… - Journal of Bone and …, 2003 - academic.oup.com
The process of bone growth, regeneration, and remodeling is mediated, in part, by the
immediate cell‐matrix environment. Osteoblast stimulating factor‐1 (OSF‐1), more …