Background Progression of structural lung disease (SLD) is a major risk factor for morbidity
in patients with cystic fibrosis (CF). We studied changes in SLD and correlations with …

Background Knowledge of between-session variability of nitrogen multiple-breath washout
(N 2 MBW) indices is crucial when designing longitudinal interventional studies and in …

Rationale: Nitrogen multiple‐breath washout (N2 MBW) is a promising tool for assessing
early lung damage in children with chronic obstructive pulmonary disease, but it can be a …

Background The quality of chest Computed Tomography (CT) images in children is
dependent upon a sufficient breath hold during CT scanning. This study evaluates the …

Background: Computed tomography (CT) of the lungs is the gold standard for assessing the
extent of structural changes in the lungs. Spirometry-controlled chest CT (SCCCT) has …

Hypothesis Using increase in the lung clearance index (LCI) as a trigger for bronchoalveolar
lavage (BAL) and associated antimicrobial treatment might benefit clinical outcomes in …

Background In this pilot study we investigated daytime variation of multiple breath nitrogen
washout (N2MBW) measures in children with clinically stable cystic fibrosis. To our …

Aim: The aim of this study was to evaluate the safety and short‐term outcome of our
management of asymptomatic children with antenatally diagnosed congenital thoracic …

Rationale: Multiple breath washout (MBW) is increasingly used as a highly sensitive
endpoint in cystic fibrosis (CF) studies. However, repeatability of output variables such as …

Objective: To assess risk and risk factors for RSV hospitalisation and determinants of
severity of RSV disease in children with heart disease. Methods: By using a database on …