User profiles for "author:Senthil Senniappan"
Dr Senthil SenniappanVerified email at doctors.org.uk Cited by 1692 |
Hyperinsulinaemic hypoglycaemia: genetic mechanisms, diagnosis and management
Hyperinsulinaemic hypoglycaemia (HH) is due to the unregulated secretion of insulin from
pancreatic β-cells. A rapid diagnosis and appropriate management of these patients is …
pancreatic β-cells. A rapid diagnosis and appropriate management of these patients is …
Childhood obesity: A review of current and future management options
LJ Apperley, J Blackburn… - Clinical …, 2022 - Wiley Online Library
Obesity is becoming increasingly prevalent in paediatric populations worldwide. In addition
to increasing prevalence, the severity of obesity is also continuing to rise. Taken together …
to increasing prevalence, the severity of obesity is also continuing to rise. Taken together …
Congenital hyperinsulinism: recent updates on molecular mechanisms, diagnosis and management
D Giri, K Hawton, S Senniappan - Journal of Pediatric Endocrinology …, 2022 - degruyter.com
Congenital hyperinsulinism (CHI) is a rare disease characterized by an unregulated insulin
release, leading to hypoglycaemia. It is the most frequent cause of persistent and severe …
release, leading to hypoglycaemia. It is the most frequent cause of persistent and severe …
[HTML][HTML] Sirolimus therapy in infants with severe hyperinsulinemic hypoglycemia
S Senniappan, S Alexandrescu… - … England Journal of …, 2014 - Mass Medical Soc
Hyperinsulinemic hypoglycemia is the most common cause of severe, persistent neonatal
hypoglycemia. The treatment of hyperinsulinemic hypoglycemia that is unresponsive to …
hypoglycemia. The treatment of hyperinsulinemic hypoglycemia that is unresponsive to …
[HTML][HTML] Pancreatic endocrine and exocrine function in children following near-total pancreatectomy for diffuse congenital hyperinsulinism
Context Congenital hyperinsulinism (CHI), the commonest cause of persistent
hypoglycaemia, has two main histological subtypes: diffuse and focal. Diffuse CHI, if …
hypoglycaemia, has two main histological subtypes: diffuse and focal. Diffuse CHI, if …
Novel FOXA2 mutation causes Hyperinsulinism, Hypopituitarism with Craniofacial and Endoderm-derived organ abnormalities
D Giri, ML Vignola, A Gualtieri… - Human molecular …, 2017 - academic.oup.com
Congenital hypopituitarism (CH) is characterized by the deficiency of one or more pituitary
hormones and can present alone or in association with complex disorders. Congenital …
hormones and can present alone or in association with complex disorders. Congenital …
Diagnosing childhood-onset inborn errors of metabolism by next-generation sequencing
A Ghosh, H Schlecht, LE Heptinstall… - Archives of Disease in …, 2017 - adc.bmj.com
Background Inborn errors of metabolism (IEMs) underlie a substantial proportion of
paediatric disease burden but their genetic diagnosis can be challenging using the …
paediatric disease burden but their genetic diagnosis can be challenging using the …
[HTML][HTML] Treating vitamin D deficiency in children with type I diabetes could improve their glycaemic control
D Giri, D Pintus, G Burnside, A Ghatak, F Mehta… - BMC research …, 2017 - Springer
Background and aims The relationship between vitamin D deficiency and type I DM is an
ongoing area of interest. The study aims to identify the prevalence of vitamin D deficiency in …
ongoing area of interest. The study aims to identify the prevalence of vitamin D deficiency in …
[HTML][HTML] Standardised practices in the networked management of congenital hyperinsulinism: a UK national collaborative consensus
MG Shaikh, AK Lucas-Herald, A Dastamani… - Frontiers in …, 2023 - frontiersin.org
Congenital hyperinsulinism (CHI) is a condition characterised by severe and recurrent
hypoglycaemia in infants and young children caused by inappropriate insulin over …
hypoglycaemia in infants and young children caused by inappropriate insulin over …
[HTML][HTML] The molecular mechanisms, diagnosis and management of congenital hyperinsulinism
Congenital hyperinsulinism (CHI) is the result of unregulated insulin secretion from the
pancreatic β-cells leading to severe hypoglycaemia. In these patients it is important to make …
pancreatic β-cells leading to severe hypoglycaemia. In these patients it is important to make …