T cell anergy is a tolerance mechanism in which the lymphocyte is intrinsically functionally
inactivated following an antigen encounter, but remains alive for an extended period of time …

This evidence-based clinical practice guideline is a revision of the 2004 acute otitis media
(AOM) guideline from the American Academy of Pediatrics (AAP) and American Academy of …

The rapid development of aT-cell proliferative response to foreign antigens is one essential
determinant of the capacity of the immune system to eliminate a pathogen that has invaded …

Objective Tonsillectomy is one of the most common surgical procedures in the United States,
with more than 530 000 procedures performed annually in children younger than 15 years …

T lymphocytes respond to foreign antigens both by producing protein effector molecules
known as lymphokines and by multiplying. Complete activation requires two signaling …

Background The ketogenic diet has been widely and successfully used to treat children with
drug-resistant epilepsy since the 1920s. The aim of this study was to test the efficacy of the …

We investigated the antigen specificity and presentation requirements for inactivation of T
lymphocytes in vitro and in vivo. In vitro studies revealed that splenocytes treated with the …

One of the most important conceptual breakthroughs in cellular im munology during the
1970s was the realization that the influence of gene products of the major histocompatibility …

Practice Guidelines for the Diagnosis and Management of Group A Streptococcal
Pharyngitis | Clinical Infectious Diseases | Oxford Academic Skip to Main Content …

A role for DNA demethylation in transcriptional regulation of genes expressed in
differentiated somatic cells remains controversial. Here, we define a small region in the …