Acute myocardial infarction is a severe ischemic disease responsible for heart failure and
sudden death. Here, we show that after acute myocardial infarction in mice, mature B …

Complicated abdominal aortic aneurysm (AAA) is a major cause of mortality in elderly men.
Ang II–dependent TGF-β activity promotes aortic aneurysm progression in experimental …

Objective: Perinatal inflammation is a major risk factor for neurological deficits in preterm
infants. Several experimental studies have shown that systemic inflammation can alter the …

Our findings that PlGF is a cancer target and anti-PlGF is useful for anticancer treatment
have been challenged by Bais et al. Here we take advantage of carcinogen-induced and …

Intravascular hemolysis describes the relocalization of heme and hemoglobin (Hb) from
erythrocytes to plasma. We investigated the concept that erythrocyte membrane …

Coronavirus disease 2019 (COVID-19) predisposes to deep vein thrombosis (DVT) and
pulmonary embolism (PE) particularly in mechanically ventilated adults with severe …

Background—Increased permeability, predominantly controlled by endothelial junction
stability, is an early event in the deterioration of vascular integrity in ischemic disorders …

Nitric oxide (NO) is a powerful vasodilator, involved in both physiological functions and
pathophysiological alterations of various regulatory processes, for example, the …

Acute myocardial infarction is a common condition responsible for heart failure and sudden
death. Here, we show that following acute myocardial infarction in mice, CD8+ T …

Rationale: Cerebrovascular function is critical for brain health, and endogenous vascular
protective pathways may provide therapeutic targets for neurological disorders. S1P …