The aim of pharmacological lipid modification is to reduce low-density lipoprotein
cholesterol (LDL-C) as a means of either secondary or primary prevention of cardiovascular …

Coronary angiography has been the gold standard for determining the severity, extent and
prognosis of coronary atheromatous disease for the past 15–20 years. However, established …

By means of two different IgM-capture assays, enterovirus-specific IgM responses were
shown in 9 of 14 (64%) patients with chronic relapsing pericarditis. This finding suggests …

In a double-blind parallel group study, 46 patients with chronic stable angina were
randomized, after a 2-week placebo washout period, to 1 of 3 treatment groups for an …

Atrial fibrillation (AF) is a major cause of ischaemic stroke. The majority of these strokes can
be prevented by treatment with oral anticoagulation therapy. The advent of non-vitamin K …

Dopexamine, a new compound with postjunctional dopamine receptor activating and beta
adrenoceptor agonist properties, was given to 10 patients with chronic heart failure at …

Fifteen patients undergoing routine cardiac catheterization for investigation of chest pain
were given a single dose of 40 mg of nicorandil either sublingually (8 patients) or orally (7 …

Blood pressure and heart rate responses to oral tyramine have been measured in healthy
volunteers before and after administration of the selective monoamine oxidase B inhibitor …

Twenty patients aged between 12 months and 13 years underwent permanent pacemaker
implantation. The main indication for pacing was post-surgical atrioventricular block. The …

Renal function is known to sometimes have a significant effect on the pharmacokinetics of
drugs or drug metabolites, which are eliminated in appreciable amounts by the kidneys. For …