Activation of protein kinase C (PKC) isoforms has been implicated in the pathogenesis of
diabetic nephropathy. We showed earlier that PKC-α is activated in the kidneys of …

Purpose Particulate contamination due to infusion therapy carries a potential health risk for
intensive care patients. Methods This single-centre, prospective, randomized controlled trial …

Background In pediatric anesthesia, preoperative fasting guidelines are still often exceeded.
Objective The objective of this noninterventional clinical observational cohort study was to …

BACKGROUND Systemic inflammatory response syndrome (SIRS) is frequent after cardiac
surgery, but data on its incidence and perioperative risk factors are scarce for children with …

Background Since early antimicrobial therapy is mandatory in septic patients, immediate
diagnosis and distinction from non-infectious SIRS is essential but hampered by the …

Albuminuria in diabetic nephropathy is due to endothelial dysfunction, a loss of negative
charges in the basement membrane, and changes a of the slit-membrane diaphragm …

Purpose To examine the physical properties and chemical composition of particles captured
by in-line microfilters in critically ill children, and to investigate the inflammatory and cytotoxic …

Background and purpose Three-dimensional (3D) imaging, a recent technical innovation in
laparoscopic surgery, has been postulated to enhance depth perception and facilitate …

Background Infused particles induce thrombogenesis, impair microcirculation and modulate
immune response. We have previously shown in critically ill children, that particle-retentive …

In patients awaiting L u T x, MV and ECMO are often the last ways to create a bridge to L u T
x. Both interventions are associated with a poor posttransplant outcome and survival rate. To …