User profiles for "author:K Chester"

Kayleigh Louise Chester

University of Hertfordshire
Verified email at herts.ac.uk
Cited by 1086

The problem of acquired physiological immunity in plants

KS Chester - The Quarterly Review of Biology, 1933 - journals.uchicago.edu
W ar rE NOW come to the most interesting and practically most important aspect of the
problem of acquired immunity, namely the acquired immunity displayed in nature. Abundant …

Antibody–drug conjugates–a perfect synergy

JR Adair, PW Howard, JA Hartley… - Expert opinion on …, 2012 - Taylor & Francis
Introduction: There is a great unmet need for effective new treatments in cancer, which
continues to be a major cause of death. Antibody–drug conjugates (ADCs) are emerging …

Is there a link between overactive bladder and the metabolic syndrome in women? A systematic review of observational studies

…, L Cardozo, C Chapple, K Chester… - … journal of clinical …, 2015 - Wiley Online Library
Objectives To conduct a systematic review to determine whether there is an association
between metabolic syndrome (MetS) and lower urinary tract symptoms (LUTS) or overactive …

Developing and validating the Communication Function Classification System for individuals with cerebral palsy

MJC Hidecker, N Paneth… - … Medicine & Child …, 2011 - Wiley Online Library
Aim The purpose of this study was to create and validate the Communication Function
Classification System (CFCS) for children with cerebral palsy (CP), for use by a wide variety …

Stromal features are predictive of disease mortality in oral cancer patients

D Marsh, K Suchak, KA Moutasim… - The Journal of …, 2011 - Wiley Online Library
Worldwide, approximately 405 000 cases of oral cancer (OSCC) are diagnosed each year,
with a rising incidence in many countries. Despite advances in surgery and radiotherapy …

The role of extracellular spacer regions in the optimal design of chimeric immune receptors: evaluation of four different scFvs and antigens

RD Guest, RE Hawkins, N Kirillova… - Journal of …, 2005 - journals.lww.com
Human peripheral blood lymphocytes can be transduced to express antigen-dependent
CD3ζ chimeric immune receptors (CIRs), which function independently of the T-cell receptor …

[HTML][HTML] The clinical efficacy of first-generation carcinoembryonic antigen (CEACAM5)-specific CAR T cells is limited by poor persistence and transient pre …

FC Thistlethwaite, DE Gilham, RD Guest… - Cancer Immunology …, 2017 - Springer
The primary aim of this clinical trial was to determine the feasibility of delivering first-
generation CAR T cell therapy to patients with advanced, CEACAM5+ malignancy …

Cross-national time trends in bullying victimization in 33 countries among children aged 11, 13 and 15 from 2002 to 2010

KL Chester, M Callaghan, A Cosma… - … European Journal of …, 2015 - academic.oup.com
Background: Bullying among children and adolescents is a public health concern;
victimization is associated with psychological and physical health problems. The purpose of …

Effects of high‐intensity resistance training in patients with rheumatoid arthritis: A randomized controlled trial

AB Lemmey, SM Marcora, K Chester… - Arthritis Care & …, 2009 - Wiley Online Library
Objective To confirm, in a randomized controlled trial (RCT), the efficacy of high‐intensity
progressive resistance training (PRT) in restoring muscle mass and function in patients with …

Clinical evidence of efficient tumor targetting based on single–chain Fv antibody selected from a combinatorial library

RHJ Begent, MJ Verhaar, KA Chester, JL Casey… - Nature Medicine, 1996 - nature.com
We present a system for cancer targeting based on single–chain Fv (scFv) antibodies
selected from combinatorial libraries, produced in bacteria and purified by using an …