Background: Optimal nutritional choices are linked with better health, but many current
interventions to improve diet have limited effect. We tested the hypothesis that providing …

Aims To define by amalgamation of data obtained in contemporaneous case‐control
studies, the risks associated with individual nonaspirin nonsteroidal anti‐inflammatory drugs …

Summary Background Pathogenic mitochondrial DNA (mtDNA) mutations are found in at
least one in 8000 individuals. No effective treatment for mtDNA disorders is available …

Evidence from randomized controlled clinical trials is widely accepted as the only sound
basis for assessing the efficacy of new medical treatments. Statistical methods play a key …

As we have previously described, 1 the statistical term interaction relates to the non-
independence of the effects of two variables on the outcome of interest. For example, in a …

Improving lifestyle behaviours has considerable potential for reducing the global burden of
non-communicable diseases, promoting better health across the life-course and increasing …

BackgroundIn order to obtain a measure of nutrient intake, a measure or estimate of the
amount of food consumed is required. Weighing foods imposes a large burden on subjects …

Background To compare the efficacy of the Newcastle infant dialysis and ultrafiltration
system (Nidus) with peritoneal dialysis (PD) and conventional haemodialysis (HD) in infants …

Online dietary assessment tools offer a convenient, low cost alternative to traditional dietary
assessment methods such as weighed records and face-to-face interviewer-led 24-h recalls …

In several types of study we may want to examine the consistency of an observed relation
across two or more subgroups of the individuals studied. For example, in a clinical trial we …