[HTML][HTML] Chipster: user-friendly analysis software for microarray and other high-throughput data

MA Kallio, JT Tuimala, T Hupponen, P Klemelä… - BMC genomics, 2011 - Springer
Background The growth of high-throughput technologies such as microarrays and next
generation sequencing has been accompanied by active research in data analysis …

[HTML][HTML] Microbial community analysis reveals high level phylogenetic alterations in the overall gastrointestinal microbiota of diarrhoea-predominant irritable bowel …

…, A Lyra, E Malinen, J Aarnikunnas, J Tuimala… - BMC …, 2009 - Springer
Background A growing amount of scientific evidence suggests that microbes are involved in
the aetiology of irritable bowel syndrome (IBS), and the gastrointestinal (GI) microbiota of …

[HTML][HTML] APOE ε4 associates with increased risk of severe COVID-19, cerebral microhaemorrhages and post-COVID mental fatigue: a Finnish biobank, autopsy and …

…, J Martola, M Pöyhönen, M Kero, J Tuimala… - Acta neuropathologica …, 2021 - Springer
Apolipoprotein E ε4 allele (APOE4) has been shown to associate with increased
susceptibility to SARS-CoV-2 infection and COVID-19 mortality in some previous genetic …

[HTML][HTML] Faecal Microbiota Composition in Adults Is Associated with the FUT2 Gene Determining the Secretor Status

P Wacklin, J Tuimala, J Nikkilä, S Tims, H Mäkivuokko… - PloS one, 2014 - journals.plos.org
The human intestine is colonised with highly diverse and individually defined microbiota,
which likely has an impact on the host well-being. Drivers of the individual variation in the …

Extracellular membrane vesicles from umbilical cord blood-derived MSC protect against ischemic acute kidney injury, a feature that is lost after inflammatory …

…, M Aatonen, S Kilpinen, J Tuimala… - Journal of …, 2013 - Taylor & Francis
Background Mesenchymal stromal cells (MSC) are shown to have a great therapeutic
potential in many immunological disorders. Currently the therapeutic effect of MSCs is …

Long-term trends in phytoplankton composition in the western and central Baltic Sea

N Wasmund, J Tuimala, S Suikkanen… - Journal of Marine …, 2011 - Elsevier
The phytoplankton biomass data of the period 1979–2005 of the Belt Sea area and the
Baltic Proper, separated into spring, summer and autumn data, were checked for trends …

Genetic polymorphisms of DNA repair and xenobiotic-metabolizing enzymes: role in mutagen sensitivity

J Tuimala, G Szekely, S Gundy, A Hirvonen… - …, 2002 - academic.oup.com
Mutagen sensitivity, measuring the extent of chromosome damage induced by an in vitro
treatment of peripheral lymphocytes with bleomycin, has been associated with an increased …

The genome of pseudocowpoxvirus: comparison of a reindeer isolate and a reference strain

M Hautaniemi, N Ueda, J Tuimala… - Journal of general …, 2010 - microbiologyresearch.org
Parapoxviruses (PPV), of the family Poxviridae, cause a pustular cutaneous disease in
sheep and goats (orf virus, ORFV) and cattle (pseudocowpoxvirus, PCPV and bovine …

[HTML][HTML] Lewy-related pathology exhibits two anatomically and genetically distinct progression patterns: a population-based study of Finns aged 85+

A Raunio, K Kaivola, J Tuimala, M Kero, M Oinas… - Acta …, 2019 - Springer
According to a generally accepted concept Lewy-related pathology (LRP) follows
hierarchical caudo-rostral progression. LRP is also frequently present concomitantly with …

[HTML][HTML] Enhancing the adoption of digital public services: Evidence from a large-scale field experiment

A Hyytinen, J Tuimala, M Hammar - Government Information Quarterly, 2022 - Elsevier
Governments increasingly digitalize the provision of their public services, but these efforts
fail to generate expected social benefits if the services remain underutilized. We use a large …