Higher vs lower positive end-expiratory pressure in patients with acute lung injury and acute respiratory distress syndrome: systematic review and meta-analysis
Context Trials comparing higher vs lower levels of positive end-expiratory pressure (PEEP)
in adults with acute lung injury or acute respiratory distress syndrome (ARDS) have been …
in adults with acute lung injury or acute respiratory distress syndrome (ARDS) have been …
The effect of oral antidiabetic agents on A1C levels: a systematic review and meta-analysis
D Sherifali, K Nerenberg, E Pullenayegum… - Diabetes …, 2010 - Am Diabetes Assoc
OBJECTIVE Previous reviews of the effect of oral antidiabetic (OAD) agents on A1C levels
summarized studies with varying designs and methodological approaches. Using …
summarized studies with varying designs and methodological approaches. Using …
[HTML][HTML] The relative efficacy of nine osteoporosis medications for reducing the rate of fractures in post-menopausal women
RB Hopkins, R Goeree, E Pullenayegum… - BMC Musculoskeletal …, 2011 - Springer
Background In the absence of head-to-head trials, indirect comparisons of randomized
placebo-controlled trials may provide a viable option to assess relative efficacy. The purpose …
placebo-controlled trials may provide a viable option to assess relative efficacy. The purpose …
Physical activity and other health-risk behaviors during the transition into early adulthood: a longitudinal cohort study
BACKGROUND: Research consistently demonstrates that physical activity declines with
age. However, such declines do not occur linearly. The transition into early adulthood is one …
age. However, such declines do not occur linearly. The transition into early adulthood is one …
Despite 2009 guidelines, few women report being counseled correctly about weight gain during pregnancy
SD McDonald, E Pullenayegum, VH Taylor… - American journal of …, 2011 - Elsevier
OBJECTIVE: The purpose of this study was to determine the information that pregnant
women report receiving when being counseled about weight gain and the risks of …
women report receiving when being counseled about weight gain and the risks of …
[HTML][HTML] A time trade-off-derived value set of the EQ-5D-5L for Canada
Background: The 5-level version of the EQ-5D (EQ-5D-5L) was recently developed. A
number of preference-based scoring systems are being developed for several countries …
number of preference-based scoring systems are being developed for several countries …
Long-term DHEA replacement in primary adrenal insufficiency: a randomized, controlled trial
EM Gurnell, PJ Hunt, SE Curran… - The Journal of …, 2008 - academic.oup.com
Abstract Context: Dehydroepiandrosterone (DHEA) and DHEA sulfate (DHEAS) are the
major circulating adrenal steroids and substrates for peripheral sex hormone biosynthesis …
major circulating adrenal steroids and substrates for peripheral sex hormone biosynthesis …
[HTML][HTML] United States valuation of EQ-5D-5L health states using an international protocol
Objective To derive a US-based value set for the EQ-5D-5L questionnaire using an
international, standardized protocol developed by the EuroQol Group. Methods …
international, standardized protocol developed by the EuroQol Group. Methods …
[HTML][HTML] Potentiating cancer immunotherapy using an oncolytic virus
Oncolytic viruses (OVs) are highly immunogenic and this limits their use in immune-
competent hosts. Although immunosuppression may improve viral oncolysis, this gain is …
competent hosts. Although immunosuppression may improve viral oncolysis, this gain is …
Analysis of health utility data when some subjects attain the upper bound of 1: are Tobit and CLAD models appropriate?
Background: Health utility data often show an apparent truncation effect, where a proportion
of individuals achieve the upper bound of 1. The Tobit model and censored least absolute …
of individuals achieve the upper bound of 1. The Tobit model and censored least absolute …