The definition of clinically significant hypoglycemia remains one of the most confused and
contentious issues in contemporary neonatology. In this article, some of the reasons for …

Dunne, Mark J., Karen E. Cosgrove, Ruth M. Shepherd, Albert Aynsley-Green, and Keith J.
Lindley. Hyperinsulinism in Infancy: From Basic Science to Clinical Disease. Physiol Rev 84 …

Background Unprecedented changes in both the scale and the complexity of international
migration have led to international concern and controversy over the assessment of age in …

A female infant of nonconsanguineous Indian parents presented at 4 months with a
hypoglycemic convulsion. Further episodes of hypoketotic hypoglycemia were associated …

Usher syndrome type 1 describes the association of profound, congenital sensorineural
deafness, vestibular hypofunction and childhood onset retinitis pigmentosa 1. It is an …

Persistent hyperinsulinemic hypoglycemia of infancy is caused by inappropriate and
excessive secretion of insulin. Although the disease is rare in outbred communities …

Persistent hyperinsulinemic hypoglycemia of infancy (PHHI) is a disorder of childhood
associated with inappropriate hypersecretion of insulin by the pancreas. The pathogenesis …

Glycogen storage disease type 0 (GSD-0) is a rare form of fasting hypoglycemia presenting
in infancy or early childhood and accompanied by high blood ketones and low alanine and …

A discussion meeting was held on October 17, 1989, to address the current status of the
definition of significant hypoglycemia in infancy, especially in the normal-and low-birth …

Islet amyloid polypeptide (IAPP) and insulin are expressed in the β-cells of the islets of
Langerhans. They are co-secreted in response to changes in glucose concentration, and …