Abstract
Prevention of type I diabetes is now a practical goal thanks to the ability to define confidently a high-risk group and the success of preventive strategies in animal models. We describe here a pilot trial of low-dose insulin to prevent diabetes in relatives of patients with type I diabetes.
MeSH terms
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Adolescent
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Adult
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Autoantibodies / blood
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Blood Glucose / analysis
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Child
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Diabetes Mellitus, Type 1 / blood
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Diabetes Mellitus, Type 1 / drug therapy*
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Diabetes Mellitus, Type 1 / epidemiology
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Female
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Follow-Up Studies
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Glucose Tolerance Test
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Humans
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Infusions, Intravenous
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Injections, Subcutaneous
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Insulin / administration & dosage
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Insulin / pharmacology
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Insulin / therapeutic use*
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Insulin Antibodies / blood
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Islets of Langerhans / drug effects
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Islets of Langerhans / immunology
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Islets of Langerhans / metabolism
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Life Style
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Life Tables
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Male
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Mass Screening
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Pedigree
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Pilot Projects
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Primary Prevention / methods
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Primary Prevention / standards*
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Risk Factors
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Treatment Outcome
Substances
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Autoantibodies
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Blood Glucose
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Insulin
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Insulin Antibodies