Pancolonic disease in cystic fibrosis and high-dose pancreatic enzyme therapy

J Pediatr. 1994 Oct;125(4):587-9. doi: 10.1016/s0022-3476(94)70014-1.

Abstract

We describe a child with cystic fibrosis who was treated with high-dose pancreatic enzyme replacement therapy and who had a prominent ascending colon stricture with submucosal fibrosis. Unlike prior reported cases, this patient's disease was more extensive, involving the entire colon, and was associated with chylous ascites.

Publication types

  • Case Reports

MeSH terms

  • Child, Preschool
  • Chronic Disease
  • Chylous Ascites / etiology
  • Colon / pathology*
  • Colonic Diseases / etiology*
  • Cystic Fibrosis / complications*
  • Cystic Fibrosis / drug therapy
  • Diarrhea / etiology
  • Fibrosis / etiology
  • Humans
  • Intestinal Obstruction / etiology*
  • Lipase / administration & dosage
  • Lipase / adverse effects*
  • Male
  • Pancreatic Extracts / administration & dosage
  • Pancreatic Extracts / adverse effects*
  • Pancrelipase

Substances

  • Pancreatic Extracts
  • Pancrelipase
  • Lipase