Effects of oral contraceptives and obesity on protein C antigen

Thromb Haemost. 1985 Apr 22;53(2):198-9.

Abstract

In 24 women using oral contraceptives, protein C antigen was higher than in 24 women of the same age and of the same degree of obesity who were not using OC. In the pooled data for all 48 women, there was an increase in protein C of about 1% (of standard) for each 1.0 mm increase in skinfold thickness. Protein C tends to be high rather than low in circumstances predisposing to thrombosis.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Contraceptives, Oral / adverse effects*
  • Contraceptives, Oral, Hormonal / adverse effects*
  • Estrogens / adverse effects
  • Factor VII / metabolism
  • Female
  • Glycoproteins / blood*
  • Humans
  • Obesity / blood*
  • Progesterone Congeners / adverse effects
  • Protein C
  • Skinfold Thickness

Substances

  • Contraceptives, Oral
  • Contraceptives, Oral, Hormonal
  • Estrogens
  • Glycoproteins
  • Progesterone Congeners
  • Protein C
  • Factor VII