Etiology and mortality of status epilepticus in children. A recent update

Arch Neurol. 1989 Jan;46(1):74-6. doi: 10.1001/archneur.1989.00520370076023.

Abstract

We reviewed the medical records of 218 episodes of status epilepticus in 193 children who were admitted to the hospital between 1983 and 1987. Of the episodes, 61% were in boys and 39% in girls, with an age range of 1 month to 14 years (average, 3.2 years). The majority of episodes (73%) occurred in patients who were less than 5 years old, with 61% less than 3 years old and 28% less than 1 year old. Status epilepticus as the initial seizure occurred in 71% of episodes. In patients under 1 year of age, 75% of episodes were associated with acute causes (bacterial meningitis in 28% and electrolyte disorders in 30%), and 23% were idiopathic (19% associated with fever). In children less than 3 years old, 47% of episodes had an acute cause, 9% had a previously known seizure disorder, and 32% were idiopathic (30% associated with fever). In patients older than 3 years, 28% of episodes were associated with acute causes, 38% were known epileptics, and 13% were idiopathic (11% had fever). Overall mortality was 6%, with 1% of all episodes ending in death during the presenting seizure. We conclude that the etiology of status epilepticus is age related, with acute causes being more common in patients with a younger age at presentation. When our data are compared with other large studies in children, it appears that mortality associated with status epilepticus has decreased.

MeSH terms

  • Acute Disease
  • Age Factors
  • Bacterial Infections / complications
  • Central Nervous System Diseases / complications
  • Child
  • Child, Preschool
  • Epilepsy / complications
  • Female
  • Fever / complications
  • Humans
  • Infant
  • Male
  • Metabolic Diseases / complications
  • Status Epilepticus / etiology*
  • Status Epilepticus / mortality*