Abstract
The incidence of invasive Streptococcus pneumoniae and Haemophilus influenzae type b infections in the sickle cell disease population has declined. In this report, we determine the predominant organisms responsible for bloodstream infections in a pediatric sickle cell disease population during the postheptavalent conjugate vaccine era. Central venous access device associated infections are a new burden to efforts aimed at preventing bloodstream infections in this population.
MeSH terms
-
Adolescent
-
Anemia, Sickle Cell / blood
-
Anemia, Sickle Cell / epidemiology*
-
Anemia, Sickle Cell / microbiology*
-
Anti-Bacterial Agents / pharmacology
-
Anti-Bacterial Agents / therapeutic use
-
Bacteremia / complications
-
Bacteremia / drug therapy
-
Bacteremia / epidemiology*
-
Bacteria / classification
-
Bacteria / drug effects
-
Bacteria / isolation & purification
-
Catheterization, Central Venous
-
Child
-
Child, Preschool
-
Humans
-
Incidence
-
Infant
-
Philadelphia / epidemiology
-
Retrospective Studies
-
Risk Factors