Recent research on inhaled corticosteroids and growth

Curr Opin Endocrinol Diabetes Obes. 2012 Feb;19(1):53-6. doi: 10.1097/MED.0b013e32834edab5.

Abstract

Purpose of review: Description of recent studies evaluating growth and inhaled corticosteroids.

Recent findings: Corticosteroids are the gold standard of asthma maintenance treatment, but effects on growth remain controversial. This is a review of recent research in this area, which has focused on medications causing less adrenal suppression as well as alternative regimens for chronic illness such as asthma.

Summary: The use of newer corticosteroids and regimens shows short-term evidence of minimal growth effects without worsening of asthma control.

Publication types

  • Review

MeSH terms

  • Administration, Inhalation
  • Adrenal Cortex Hormones / administration & dosage
  • Adrenal Cortex Hormones / adverse effects*
  • Anti-Asthmatic Agents / administration & dosage
  • Anti-Asthmatic Agents / adverse effects*
  • Asthma / complications
  • Asthma / drug therapy*
  • Body Height / drug effects*
  • Bone Density / drug effects
  • Child
  • Female
  • Growth Disorders / chemically induced*
  • Humans
  • Male

Substances

  • Adrenal Cortex Hormones
  • Anti-Asthmatic Agents