Abstract
Adenosine monophosphate, inosine monophosphate, inosine, adenosine, guanosine, adenine, guanine, hypoxanthine, xanthine, uric acid and pyrimidine bases were determined in the CSF of 18 children after simple febrile seizures and in a control group. There was no statistically significant difference between the two groups for any of these metabolites. This suggests that simple febrile seizures neither significantly disturb the metabolism of nucleotides, nucleosides or bases, nor significantly deplete neuron adenosine triphosphate ATP levels.
MeSH terms
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Adenine / cerebrospinal fluid
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Adenosine / cerebrospinal fluid
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Adenosine Monophosphate / cerebrospinal fluid
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Child, Preschool
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Cytosine / cerebrospinal fluid
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Female
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Guanine / cerebrospinal fluid
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Guanosine / cerebrospinal fluid
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Humans
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Hypoxanthine
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Hypoxanthines / cerebrospinal fluid
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Infant
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Inosine / cerebrospinal fluid
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Inosine Monophosphate / cerebrospinal fluid
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Male
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Purines / cerebrospinal fluid*
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Pyrimidine Nucleosides / cerebrospinal fluid*
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Seizures, Febrile / cerebrospinal fluid*
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Thymine / cerebrospinal fluid
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Uracil / cerebrospinal fluid
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Uric Acid / cerebrospinal fluid
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Xanthine
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Xanthines / cerebrospinal fluid
Substances
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Hypoxanthines
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Purines
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Pyrimidine Nucleosides
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Xanthines
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Guanosine
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Inosine Monophosphate
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Xanthine
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Uric Acid
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Hypoxanthine
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Adenosine Monophosphate
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Uracil
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Inosine
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Guanine
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Cytosine
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Adenine
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Adenosine
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Thymine