Ketoacidosis and hyperosmolarity as first symptoms of type 1 diabetes mellitus following ingestion of high-carbohydrate-containing fluids

J Pediatr Endocrinol Metab. 1999 Sep-Oct;12(5):691-4. doi: 10.1515/jpem.1999.12.5.691.

Abstract

The concomitant occurrence of diabetic ketoacidosis and hyperosmolarity is reported in two children, as early symptoms of misdiagnosed type 1 diabetes mellitus. The precipitating factor for both severe metabolic abnormalities was the ingestion of a large amount of high-carbohydrate-containing fluids, a few days before admission. A similar situation has never been reported before in the literature. A successful therapeutic scheme is described.

Publication types

  • Case Reports

MeSH terms

  • Blood Glucose / metabolism
  • Carbohydrates*
  • Child
  • Diabetes Mellitus, Type 1 / diagnosis*
  • Diabetes Mellitus, Type 1 / therapy
  • Diabetic Ketoacidosis / chemically induced
  • Diabetic Ketoacidosis / metabolism*
  • Diabetic Ketoacidosis / therapy
  • Fluid Therapy
  • Humans
  • Hypoglycemic Agents / administration & dosage
  • Hypoglycemic Agents / therapeutic use
  • Insulin / administration & dosage
  • Insulin / therapeutic use
  • Insulin Infusion Systems
  • Male
  • Solutions
  • Water-Electrolyte Imbalance / chemically induced
  • Water-Electrolyte Imbalance / metabolism*
  • Water-Electrolyte Imbalance / therapy

Substances

  • Blood Glucose
  • Carbohydrates
  • Hypoglycemic Agents
  • Insulin
  • Solutions