Functions of CD40 on B cells, dendritic cells and other cells
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2024, Seminars in Radiation OncologyExtensive involvement of CD40 and CD154 costimulators in multiple T cell-mediated responses in a perciform fish Larimichthys crocea
2022, Developmental and Comparative ImmunologyAn optimally designed anti-human CD40 antibody with potent B cell suppression for the treatment of autoimmune diseases
2021, International Journal of PharmaceuticsCitation Excerpt :CD40-CD40L interactions play a crucial role in T-dependent B-cell costimulation (Elgueta et al., 2009). CD40 is a 48-kDa type I membrane glycoprotein of the tumor necrosis factor (TNF) receptor superfamily expressed on B cells, dendritic cells, monocytes, macrophages, fibroblasts, endothelial cells, and epithelial cells (Banchereau et al., 1995; Bourgeois et al., 2002; Lee et al., 2014; vanKooten and Banchereau, 2000, 1997). Since its discovery on bladder carcinoma cells in 1985 by Paulie et al. (Paulie et al., 1985), CD40′s function has been extensively studied.
The CD40-CD40L axis: Current and future implications in clinical immunology
2021, Revue de Medecine Interne
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